2-Methoxyphenylacetic acid → 2-(2-Methoxyphenyl)propanoic acid

HRID 902735Notes

Reaction equation

HRID 902735 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:9][C:10]([OH:12])=[O:11].Cl[C:14]1C=CC=CC=1C(C)C(O)=O>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]([CH3:14])[C:10]([OH:12])=[O:11]

Participants

3

Reactant 2

HCID 71342-Methoxyphenylacetic acidHCID 126365742-(2-Chlorophenyl)propanoic acid

Product 1

HCID 44534652-(2-Methoxyphenyl)propanoic acidYield 39%

Procedure

The titled compound was prepared from o-methoxyphenylacetic acid in 39% yield in the same manner as the preparation of 2-(2-Chlorophenyl)propionic acid in Example 184a.

Sources & evidence

ORD record
ord-f3084eaa0f034a3e9865ade9955e992c
Source dataset
uspto-grants-2008_04
Patent number
US07365085B2

Reaction notes

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