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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 902738Generated: October 31, 2026

N-(2-[2-Chlorophenyl]-propyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carbomethoxymethylenephenoxy)propylamine → N-(2-[2-Methoxyphenyl]-propyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carbomethoxymethylenephenoxy)propylamine

https://huagongshe.com/reaction/902738

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-[2-Chlorophenyl]-propyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carbomethoxymethylenephenoxy)propylamineHCID 69253617—
ReactantN-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-methoxyphenyl)propylamineHCID 69253869—
ProductN-(2-[2-Methoxyphenyl]-propyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carbomethoxymethylenephenoxy)propylamineHCID 6925130690%

Reaction Steps

The titled compound was prepared from N-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-methoxyphenyl)propylamine in 90% yield in the same manner as the preparation of N-(2-[2-Chlorophenyl]-propyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carbomethoxymethylenephenoxy)propylamine in Example 184f. MS (ESI) 564 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07365085B2
Source datasetuspto-grants-2008_04
ORD IDord-145bf24e28bc4ab1889f745daf4cb9ed
Source noteuspto-grants-2008_04