HRID902743

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(CN(CCCOC1=CC=CC(=CC(=O)O)C1)Cc1cccc(C(F)(F)F)c1Cl)c1ccccc1Cl

HCID69251488

未命名化合物

结构：COC(=O)C=C1C=CC=C(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(C)c2ccc(OC)cc2)C1

HCID69252286

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(C(C)CN(CCCOC2=CC=CC(=CC(=O)O)C2)Cc2cccc(C(F)(F)F)c2Cl)cc1.Cl

HCID131726850

未命名化合物

收率 66%

PROCEDURE

实验过程

The titled compound was prepared from N-(2-[4-methoxyphenyl]-propyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carbomethoxymethylenephenoxy)propylamine in 66% yield in the same manner as the preparation of N-(2-[2-Chlorophenyl]-propyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carboxymethylenephenoxy)propylamine in Example 184g. MS (ESI) 550 (MH+)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0d47b1e4a86041f88b1aa6da5bf36f8a
来源数据集: uspto-grants-2008_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07365085B2
来源说明: uspto-grants-2008_04

反应 SMILES

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]([CH3:39])[CH2:10][N:11]([CH2:24][CH2:25][CH2:26][O:27][C:28]2[CH2:29][C:30](=[CH:34][C:35]([O:37]C)=[O:36])[CH:31]=[CH:32][CH:33]=2)[CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([F:22])([F:21])[F:20])[C:14]=2[Cl:23])=[CH:5][CH:4]=1.ClC1C=CC=CC=1C(C)CN(CCCOC1CC(=CC(O)=O)C=CC=1)CC1C=CC=C(C(F)(F)F)C=1Cl>>[ClH:23].[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH:9]([CH3:39])[CH2:10][N:11]([CH2:24][CH2:25][CH2:26][O:27][C:28]2[CH2:29][C:30](=[CH:34][C:35]([OH:37])=[O:36])[CH:31]=[CH:32][CH:33]=2)[CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([F:22])([F:20])[F:21])[C:14]=2[Cl:23])=[CH:7][CH:8]=1