HRID902751

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)C=C1C=CC=C(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(CC(C)C)c2ccccc2)C1

HCID69252119

未命名化合物

结构：COc1ccc(C(C)CN(CCCOC2=CC=CC(=CC(=O)O)C2)Cc2cccc(C(F)(F)F)c2Cl)cc1.Cl

HCID131726850

未命名化合物

PRODUCTS

生成物

结构：CC(C)CC(CN(CCCOC1=CC=CC(=CC(=O)O)C1)Cc1cccc(C(F)(F)F)c1Cl)c1ccccc1.Cl

HCID131726851

未命名化合物

收率 74%

PROCEDURE

实验过程

The titled compound was prepared from N-(2-phenyl-4-methylpentyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carbomethoxymethylenephenoxy)propylamine in 74% yield in the same manner as the preparation of N-(2-[4-Methoxyphenyl]-propyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carboxymethylenephenoxy)propylamine, hydrochloride in Example 188f. MS (ESI) 562 (MH+)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1689ef35220b4841bf95a72fce20be55
来源数据集: uspto-grants-2008_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07365085B2
来源说明: uspto-grants-2008_04

反应 SMILES

[C:1]1([CH:7]([CH2:37][CH:38]([CH3:40])[CH3:39])[CH2:8][N:9]([CH2:22][CH2:23][CH2:24][O:25][C:26]2[CH2:27][C:28](=[CH:32][C:33]([O:35]C)=[O:34])[CH:29]=[CH:30][CH:31]=2)[CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([C:17]([F:20])([F:19])[F:18])[C:12]=2[Cl:21])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.COC1C=CC(C(C)CN(CCCOC2CC(=CC(O)=O)C=CC=2)CC2C=CC=C(C(F)(F)F)C=2Cl)=CC=1>>[ClH:21].[C:1]1([CH:7]([CH2:37][CH:38]([CH3:40])[CH3:39])[CH2:8][N:9]([CH2:22][CH2:23][CH2:24][O:25][C:26]2[CH2:27][C:28](=[CH:32][C:33]([OH:35])=[O:34])[CH:29]=[CH:30][CH:31]=2)[CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([C:17]([F:18])([F:20])[F:19])[C:12]=2[Cl:21])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1