4-(Chloromethyl)benzoyl chloride → HCID 11399047, compound

HRID 902787Notes

Reaction equation

HRID 902787 reaction equation
[O:1]([C:8]1[CH:15]=[CH:14][C:11]([CH2:12][NH2:13])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:17][C:18]1[CH:26]=[CH:25][C:21]([C:22](Cl)=[O:23])=[CH:20][CH:19]=1.[CH:27]1([C:33](Cl)=[O:34])[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]1.[NH2:36][C:37]1[CH:49]=[CH:48][C:40]2[O:41]C(C)(C)[O:43][C:44](=[O:45])[C:39]=2[CH:38]=1>>[CH:27]1([C:33]([N:36]([CH2:17][C:18]2[CH:26]=[CH:25][C:21]([C:22]([NH:13][CH2:12][C:11]3[CH:10]=[CH:9][C:8]([O:1][C:2]4[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=4)=[CH:15][CH:14]=3)=[O:23])=[CH:20][CH:19]=2)[C:37]2[CH:49]=[CH:48][C:40]([OH:41])=[C:39]([CH:38]=2)[C:44]([OH:45])=[O:43])=[O:34])[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]1

Participants

5

Reactant 4

HCID 701364-(Chloromethyl)benzoyl chlorideHCID 75938Cyclohexanecarbonyl chlorideHCID 2760343(4-Phenoxyphenyl)methanamineHCID 116153306-Amino-2,2-dimethyl-benzo[1,3]dioxin-4-one

Product 1

HCID 11399047HCID 11399047, compound

Procedure

The title compound was prepared following the procedure A using 4-phenoxybenzylamine, 4-(chloromethyl)benzoyl chloride, cyclohexanecarbonyl chloride and 6-amino-2,2-dimethyl-4H-1,3-benzodioxin-4-one. M+(ESI): 579.1

Sources & evidence

ORD record
ord-523f8c9b096e4105b55525bfb47ff27f
Source dataset
uspto-grants-2008_04
Patent number
US07365225B2

Reaction notes

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