4-(Chloromethyl)benzoyl chloride → HCID 11478905, compound

HRID 902791Notes

Reaction equation

HRID 902791 reaction equation
[O:1]([C:8]1[CH:15]=[CH:14][C:11]([CH2:12][NH2:13])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:17][C:18]1[CH:26]=[CH:25][C:21]([C:22](Cl)=[O:23])=[CH:20][CH:19]=1.[C:27]([C:29]1[CH:37]=[CH:36][C:32]([C:33](Cl)=[O:34])=[CH:31][CH:30]=1)#[N:28].[NH2:38][C:39]1[CH:51]=[CH:50][C:42]2[O:43]C(C)(C)[O:45][C:46](=[O:47])[C:41]=2[CH:40]=1>>[C:27]([C:29]1[CH:37]=[CH:36][C:32]([C:33]([N:38]([CH2:17][C:18]2[CH:26]=[CH:25][C:21]([C:22]([NH:13][CH2:12][C:11]3[CH:10]=[CH:9][C:8]([O:1][C:2]4[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=4)=[CH:15][CH:14]=3)=[O:23])=[CH:20][CH:19]=2)[C:39]2[CH:51]=[CH:50][C:42]([OH:43])=[C:41]([CH:40]=2)[C:46]([OH:47])=[O:45])=[O:34])=[CH:31][CH:30]=1)#[N:28]

Participants

5

Reactant 4

HCID 701364-(Chloromethyl)benzoyl chlorideHCID 801724-Cyanobenzoyl chlorideHCID 2760343(4-Phenoxyphenyl)methanamineHCID 116153306-Amino-2,2-dimethyl-benzo[1,3]dioxin-4-one

Product 1

HCID 11478905HCID 11478905, compound

Procedure

The title compound was prepared following the procedure A using 4-phenoxybenzylamine, 4-(chloromethyl)benzoyl chloride, 4-cyanobenzoyl chloride and 6-amino-2,2-dimethyl-4H-1,3-benzodioxin-4-one. M+(ESI): 598.1

Sources & evidence

ORD record
ord-4ac60d23c3ce4c0aa396ada1c32ad1d1
Source dataset
uspto-grants-2008_04
Patent number
US07365225B2

Reaction notes

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