4-(Chloromethyl)benzoyl chloride → HCID 11214986, compound

HRID 902794Notes

Reaction equation

HRID 902794 reaction equation
[O:1]([C:8]1[CH:15]=[CH:14][C:11]([CH2:12][NH2:13])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:17][C:18]1[CH:26]=[CH:25][C:21]([C:22](Cl)=[O:23])=[CH:20][CH:19]=1.[CH3:27][C:28]([CH3:33])=[CH:29][C:30](Cl)=[O:31].[NH2:34][C:35]1[CH:47]=[CH:46][C:38]2[O:39]C(C)(C)[O:41][C:42](=[O:43])[C:37]=2[CH:36]=1>>[OH:39][C:38]1[CH:46]=[CH:47][C:35]([N:34]([C:30](=[O:31])[CH:29]=[C:28]([CH3:33])[CH3:27])[CH2:17][C:18]2[CH:26]=[CH:25][C:21]([C:22]([NH:13][CH2:12][C:11]3[CH:10]=[CH:9][C:8]([O:1][C:2]4[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=4)=[CH:15][CH:14]=3)=[O:23])=[CH:20][CH:19]=2)=[CH:36][C:37]=1[C:42]([OH:43])=[O:41]

Participants

5

Reactant 4

HCID 701364-(Chloromethyl)benzoyl chlorideHCID 1023943-Methyl-2-butenoyl chlorideHCID 2760343(4-Phenoxyphenyl)methanamineHCID 116153306-Amino-2,2-dimethyl-benzo[1,3]dioxin-4-one

Product 1

HCID 11214986HCID 11214986, compound

Procedure

The title compound was prepared following the procedure A using 4-phenoxybenzylamine, 4-(chloromethyl)benzoyl chloride, 3-methylbut-2-enoyl chloride and 6-amino-2,2-dimethyl-4H-1,3-benzodioxin-4-one. M+(ESI): 551.1

Sources & evidence

ORD record
ord-19c15d7d4fb84d1486eff85a47a3848e
Source dataset
uspto-grants-2008_04
Patent number
US07365225B2

Reaction notes

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