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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 902800Generated: October 26, 2026

4-(Trifluoromethyl)benzoyl chloride → 2-Hydroxy-5-({(4-{[(4-pentylbenzyl)amino]carbonyl}benzyl)[4-(trifluoromethyl)benzoyl]amino}methyl)benzoic acid

https://huagongshe.com/reaction/902800

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)benzoyl chlorideHCID 67607—
Reactant4-(Chloromethyl)benzoyl chlorideHCID 70136—
Reactant(4-Pentylphenyl)methanamineHCID 2775785—
Reactant6-(aminomethyl)-2,2-dimethyl-4H-1,3-benzodioxin-4-one acetateHCID 67420478—
Product2-Hydroxy-5-({(4-{[(4-pentylbenzyl)amino]carbonyl}benzyl)[4-(trifluoromethyl)benzoyl]amino}methyl)benzoic acidHCID 11285093—

Reaction Steps

The title compound was prepared following the procedure A using 4-pentylbenzylamine, 4-(chloromethyl)benzoyl chloride, 4-(trifluoromethyl)benzoyl chloride and 6-(aminomethyl)-2,2-dimethyl-4H-1,3-benzodioxin-4-one acetate. M+(ESI): 633.4

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07365225B2
Source datasetuspto-grants-2008_04
ORD IDord-6ed1de33c87e4fdf89d28dc8f6da3666
Source noteuspto-grants-2008_04