3-Cyclopentylpropionyl chloride → HCID 11203726, compound

HRID 902802Notes

Reaction equation

HRID 902802 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][NH2:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[CH2:13][C:14]1[CH:22]=[CH:21][C:17]([C:18](Cl)=[O:19])=[CH:16][CH:15]=1.[CH:23]1([CH2:28][CH2:29][C:30](Cl)=[O:31])[CH2:27][CH2:26][CH2:25][CH2:24]1.C(O)(=O)C.[NH2:37][CH2:38][C:39]1[CH:51]=[CH:50][C:42]2[O:43]C(C)(C)[O:45][C:46](=[O:47])[C:41]=2[CH:40]=1>>[CH:23]1([CH2:28][CH2:29][C:30]([N:37]([CH2:38][C:39]2[CH:51]=[CH:50][C:42]([OH:43])=[C:41]([CH:40]=2)[C:46]([OH:47])=[O:45])[CH2:13][C:14]2[CH:22]=[CH:21][C:17]([C:18]([NH:11][CH2:10][CH2:9][CH2:8][CH2:7][C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)=[O:19])=[CH:16][CH:15]=2)=[O:31])[CH2:27][CH2:26][CH2:25][CH2:24]1

Participants

5

Reactant 4

HCID 660393-Cyclopentylpropionyl chlorideHCID 701364-(Chloromethyl)benzoyl chlorideHCID 83242BenzenebutanamineHCID 674204786-(aminomethyl)-2,2-dimethyl-4H-1,3-benzodioxin-4-one acetate

Product 1

HCID 11203726HCID 11203726, compound

Procedure

The title compound was prepared following the procedure A using 4-phenylbutylamine, 4-(chloromethyl)benzoyl chloride, 3-cyclopentylpropanoyl chloride and 6-(aminomethyl)-2,2-dimethyl-4H-1,3-benzodioxin-4-one acetate. M+(ESI): 557.5

Sources & evidence

ORD record
ord-03eed0f1f6054cd295c5d8c59e23ce89
Source dataset
uspto-grants-2008_04
Patent number
US07365225B2

Reaction notes

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