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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 902803Generated: October 26, 2026

(4-Pentylphenyl)methanamine → 2-hydroxy-5-({[(4-{[(4-pentylbenzyl)amino]carbonyl}-1,3-thiazol-2-yl)methyl][(2E)-3-phenylprop-2-enoyl]amino}methyl)benzoic acid

https://huagongshe.com/reaction/902803

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Pentylphenyl)methanamineHCID 2775785—
ReactantCinnamoyl ChlorideHCID 5354261—
Reactant2-(Chloromethyl)-1,3-thiazole-4-carbonyl chlorideHCID 59702456—
Reactant6-(aminomethyl)-2,2-dimethyl-4H-1,3-benzodioxin-4-one acetateHCID 67420478—
Product2-hydroxy-5-({[(4-{[(4-pentylbenzyl)amino]carbonyl}-1,3-thiazol-2-yl)methyl][(2E)-3-phenylprop-2-enoyl]amino}methyl)benzoic acidHCID 11376858—

Reaction Steps

The title compound was prepared following the procedure A using 4-pentylbenzylamine, 2-(chloromethyl)-1,3-thiazole-4-carbonyl chloride, (2E)-3-phenylacryloyl chloride and 6-(aminomethyl)-2,2-dimethyl-4H-1,3-benzodioxin-4-one acetate. M+(ESI): 598.4

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07365225B2
Source datasetuspto-grants-2008_04
ORD IDord-25978117631b49f9ae062dc3a4f18ce8
Source noteuspto-grants-2008_04