4-(Trifluoromethyl)benzoyl chloride → HCID 58693698, compound

HRID 902807Notes

Reaction equation

HRID 902807 reaction equation
[CH2:1]([C:6]1[CH:13]=[CH:12][C:9]([CH2:10][NH2:11])=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH2:4][CH3:5].Cl[CH2:15][C:16]1[CH:24]=[CH:23][C:19]([C:20](Cl)=[O:21])=[CH:18][CH:17]=1.[F:25][C:26]([F:37])([F:36])[C:27]1[CH:35]=[CH:34][C:30]([C:31](Cl)=[O:32])=[CH:29][CH:28]=1.[NH2:38][C:39]1[CH:40]=[CH:41][C:42]2[C:47](=[O:48])[O:46]C(C)(C)[O:44][C:43]=2[CH:51]=1>>[OH:44][C:43]1[CH:51]=[C:39]([N:38]([CH2:15][C:16]2[CH:24]=[CH:23][C:19]([C:20]([NH:11][CH2:10][C:9]3[CH:12]=[CH:13][C:6]([CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])=[CH:7][CH:8]=3)=[O:21])=[CH:18][CH:17]=2)[C:31](=[O:32])[C:30]2[CH:34]=[CH:35][C:27]([C:26]([F:37])([F:36])[F:25])=[CH:28][CH:29]=2)[CH:40]=[CH:41][C:42]=1[C:47]([OH:48])=[O:46]

Participants

5

Reactant 4

HCID 676074-(Trifluoromethyl)benzoyl chlorideHCID 701364-(Chloromethyl)benzoyl chlorideHCID 2775785(4-Pentylphenyl)methanamineHCID 231100727-Amino-2,2-dimethyl-4H-1,3-benzodioxine-4-one

Product 1

HCID 58693698HCID 58693698, compound

Procedure

The title compound was prepared following the procedure A using 4-pentylbenzylamine, 4-(chloromethyl)benzoyl chloride, 4-(trifluoromethyl)benzoyl chloride and 7-amino-2,2-dimethyl-4H-1,3-benzodioxin-4-one. M+(ESI): 619.3

Sources & evidence

ORD record
ord-0df7d071d1e94d5fa10421095e8c57e2
Source dataset
uspto-grants-2008_04
Patent number
US07365225B2

Reaction notes

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