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4-(Trifluoromethyl)benzoyl chloride → 2-Hydroxy-5-{{[2-(4-{[(4-phenoxybenzyl)amino]carbonyl}phenyl)-1,3-thiazol-4-yl]methyl}[4-(trifluoromethyl)benzoyl]amino}benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(Trifluoromethyl)benzoyl chloride | HCID 67607 | — |
| 反応物 | (4-Phenoxyphenyl)methanamine | HCID 2760343 | — |
| 反応物 | 6-Amino-2,2-dimethyl-benzo[1,3]dioxin-4-one | HCID 11615330 | — |
| 反応物 | 4-[4-(Chloromethyl)-1,3-thiazol-2-yl]benzoyl chloride | HCID 58693699 | — |
| 生成物 | 2-Hydroxy-5-{{[2-(4-{[(4-phenoxybenzyl)amino]carbonyl}phenyl)-1,3-thiazol-4-yl]methyl}[4-(trifluoromethyl)benzoyl]amino}benzoic acid | HCID 11297104 | — |
反応手順
The title compound was prepared following the procedure A using 4-phenoxybenzylamine, 4-[4-(chloromethyl)-1,3-thiazol-2-yl]benzoyl chloride, 4-(trifluoromethyl)benzoyl chloride and 6-amino-2,2-dimethyl-4H-1,3-benzodioxin-4-one. M+(ESI): 724.1
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07365225B2 |
| 出典データセット | uspto-grants-2008_04 |
| ORD ID | ord-eb3bd972168944c8a7d059b9f9d75ed2 |
| 出典メモ | uspto-grants-2008_04 |