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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 902812Generated: October 25, 2026

Benzoyl chloride → 5-(Benzoyl{[2-(4-{[(4-phenoxybenzyl)amino]carbonyl}phenyl)-1,3-thiazol-4-yl]methyl}amino)-2-hydroxybenzoic acid

https://huagongshe.com/reaction/902812

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl chlorideHCID 7412—
Reactant(4-Phenoxyphenyl)methanamineHCID 2760343—
Reactant6-Amino-2,2-dimethyl-benzo[1,3]dioxin-4-oneHCID 11615330—
Reactant4-[4-(Chloromethyl)-1,3-thiazol-2-yl]benzoyl chlorideHCID 58693699—
Product5-(Benzoyl{[2-(4-{[(4-phenoxybenzyl)amino]carbonyl}phenyl)-1,3-thiazol-4-yl]methyl}amino)-2-hydroxybenzoic acidHCID 11456527—

Reaction Steps

The title compound was prepared following the procedure A using 4-phenoxybenzylamine, 4-[4-(chloromethyl)-1,3-thiazol-2-yl]benzoyl chloride, benzoyl chloride and 6-amino-2,2-dimethyl-4H-1,3-benzodioxin-4-one. M+(ESI): 656.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07365225B2
Source datasetuspto-grants-2008_04
ORD IDord-099d98e83bcd4568a3b47aedc1740d14
Source noteuspto-grants-2008_04