Benzenebutanamine → HCID 11181061, compound

HRID 902818Notes

Reaction equation

HRID 902818 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][NH2:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[CH2:13][C:14]1[N:15]=[C:16]([C:19]2[CH:27]=[CH:26][C:22]([C:23](Cl)=[O:24])=[CH:21][CH:20]=2)[S:17][CH:18]=1.Cl.[CH3:29][N:30]([CH3:35])[CH2:31][C:32](Cl)=[O:33].C[O:37][C:38](=[O:49])[CH2:39][O:40][C:41]1[CH:46]=[CH:45][C:44]([CH2:47][NH2:48])=[CH:43][CH:42]=1>>[CH3:29][N:30]([CH3:35])[CH2:31][C:32]([N:48]([CH2:47][C:44]1[CH:45]=[CH:46][C:41]([O:40][CH2:39][C:38]([OH:49])=[O:37])=[CH:42][CH:43]=1)[CH2:13][C:14]1[N:15]=[C:16]([C:19]2[CH:27]=[CH:26][C:22]([C:23]([NH:11][CH2:10][CH2:9][CH2:8][CH2:7][C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)=[O:24])=[CH:21][CH:20]=2)[S:17][CH:18]=1)=[O:33]

Participants

5

Reactant 4

HCID 83242BenzenebutanamineHCID 139949912-(Dimethylamino)acetyl chloride hydrochlorideHCID 16770770Methyl [4-(aminomethyl)phenoxy]acetateHCID 586936994-[4-(Chloromethyl)-1,3-thiazol-2-yl]benzoyl chloride

Product 1

HCID 11181061HCID 11181061, compound

Procedure

The title compound was prepared following the procedure [79 [0 using 4-phenylbutylamine, 4-[4-(chloromethyl)-1,3-thiazol-2-yl]benzoyl chloride, N,N-dimethylglycyl chloride hydrochloride and methyl[4-(aminomethyl)phenoxy]acetate, acetate salt. M+(ESI): 615.2

Sources & evidence

ORD record
ord-d857bfeaa7954707bbd65e87d0c5c696
Source dataset
uspto-grants-2008_04
Patent number
US07365225B2

Reaction notes

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