Cyclohexanecarbonyl chloride → HCID 11456442, compound

HRID 902819Notes

Reaction equation

HRID 902819 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][NH2:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[CH2:13][C:14]1[N:15]=[C:16]([C:19]2[CH:27]=[CH:26][C:22]([C:23](Cl)=[O:24])=[CH:21][CH:20]=2)[S:17][CH:18]=1.[CH:28]1([C:34](Cl)=[O:35])[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1.C[O:38][C:39](=[O:50])[CH2:40][O:41][C:42]1[CH:47]=[CH:46][C:45]([CH2:48][NH2:49])=[CH:44][CH:43]=1>>[CH:28]1([C:34]([N:49]([CH2:48][C:45]2[CH:46]=[CH:47][C:42]([O:41][CH2:40][C:39]([OH:50])=[O:38])=[CH:43][CH:44]=2)[CH2:13][C:14]2[N:15]=[C:16]([C:19]3[CH:27]=[CH:26][C:22]([C:23]([NH:11][CH2:10][CH2:9][CH2:8][CH2:7][C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=4)=[O:24])=[CH:21][CH:20]=3)[S:17][CH:18]=2)=[O:35])[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1

Participants

5

Reactant 4

HCID 75938Cyclohexanecarbonyl chlorideHCID 83242BenzenebutanamineHCID 16770770Methyl [4-(aminomethyl)phenoxy]acetateHCID 586936994-[4-(Chloromethyl)-1,3-thiazol-2-yl]benzoyl chloride

Product 1

HCID 11456442HCID 11456442, compound

Procedure

The title compound was prepared following the procedure A using 4-phenylbutylamine, 4-[4-(chloromethyl)-1,3-thiazol-2-yl]benzoyl chloride, cyclohexanecarbonyl chloride and methyl[4-(aminomethyl)phenoxy]acetate, acetate salt. M+(ESI): 640.2

Sources & evidence

ORD record
ord-62c52891f6a54c6592daf074b7845686
Source dataset
uspto-grants-2008_04
Patent number
US07365225B2

Reaction notes

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