Benzenepropanoyl chloride → HCID 11763985, compound

HRID 902822Notes

Reaction equation

HRID 902822 reaction equation
[O:1]([C:8]1[CH:15]=[CH:14][C:11]([CH2:12][NH2:13])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:17][C:18]1[N:19]=[C:20]([C:23]2[CH:31]=[CH:30][C:26]([C:27](Cl)=[O:28])=[CH:25][CH:24]=2)[S:21][CH:22]=1.[C:32]1([CH2:38][CH2:39][C:40](Cl)=[O:41])[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1.C[O:44][C:45](=[O:56])[CH2:46][O:47][C:48]1[CH:53]=[CH:52][C:51]([CH2:54][NH2:55])=[CH:50][CH:49]=1>>[O:1]([C:8]1[CH:9]=[CH:10][C:11]([CH2:12][NH:13][C:27]([C:26]2[CH:30]=[CH:31][C:23]([C:20]3[S:21][CH:22]=[C:18]([CH2:17][N:55]([CH2:54][C:51]4[CH:52]=[CH:53][C:48]([O:47][CH2:46][C:45]([OH:56])=[O:44])=[CH:49][CH:50]=4)[C:40](=[O:41])[CH2:39][CH2:38][C:32]4[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=4)[N:19]=3)=[CH:24][CH:25]=2)=[O:28])=[CH:14][CH:15]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 4

HCID 64801Benzenepropanoyl chlorideHCID 2760343(4-Phenoxyphenyl)methanamineHCID 16770770Methyl [4-(aminomethyl)phenoxy]acetateHCID 586936994-[4-(Chloromethyl)-1,3-thiazol-2-yl]benzoyl chloride

Product 1

HCID 11763985HCID 11763985, compound

Procedure

The title compound was prepared following the procedure A using 4-phenoxybenzylamine, 4-[4-(chloromethyl)-1,3-thiazol-2-yl]benzoyl chloride, 3-phenylpropanoyl chloride and methyl[4-(aminomethyl)phenoxy]acetate, acetate salt. M+(ESI): 712.1

Sources & evidence

ORD record
ord-af78f9a0d076463d913650d453cae169
Source dataset
uspto-grants-2008_04
Patent number
US07365225B2

Reaction notes

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