Cyclohexanecarbonyl chloride → HCID 11216127, compound

HRID 902823Notes

Reaction equation

HRID 902823 reaction equation
[O:1]([C:8]1[CH:15]=[CH:14][C:11]([CH2:12][NH2:13])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:17][C:18]1[N:19]=[C:20]([C:23]2[CH:31]=[CH:30][C:26]([C:27](Cl)=[O:28])=[CH:25][CH:24]=2)[S:21][CH:22]=1.[CH:32]1([C:38](Cl)=[O:39])[CH2:37][CH2:36][CH2:35][CH2:34][CH2:33]1.C[O:42][C:43](=[O:54])[CH2:44][O:45][C:46]1[CH:51]=[CH:50][C:49]([CH2:52][NH2:53])=[CH:48][CH:47]=1>>[CH:32]1([C:38]([N:53]([CH2:52][C:49]2[CH:50]=[CH:51][C:46]([O:45][CH2:44][C:43]([OH:54])=[O:42])=[CH:47][CH:48]=2)[CH2:17][C:18]2[N:19]=[C:20]([C:23]3[CH:31]=[CH:30][C:26]([C:27]([NH:13][CH2:12][C:11]4[CH:10]=[CH:9][C:8]([O:1][C:2]5[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=5)=[CH:15][CH:14]=4)=[O:28])=[CH:25][CH:24]=3)[S:21][CH:22]=2)=[O:39])[CH2:37][CH2:36][CH2:35][CH2:34][CH2:33]1

Participants

5

Reactant 4

HCID 75938Cyclohexanecarbonyl chlorideHCID 2760343(4-Phenoxyphenyl)methanamineHCID 16770770Methyl [4-(aminomethyl)phenoxy]acetateHCID 586936994-[4-(Chloromethyl)-1,3-thiazol-2-yl]benzoyl chloride

Product 1

HCID 11216127HCID 11216127, compound

Procedure

The title compound was prepared following the procedure A using 4-phenoxybenzylamine, 4-[4-(chloromethyl)-1,3-thiazol-2-yl]benzoyl chloride, cyclohexanecarbonyl chloride and methyl[4-(aminomethyl)phenoxy]acetate, acetate salt. M+(ESI): 690.2

Sources & evidence

ORD record
ord-7eb4db8892234b208e3feb21b89801f9
Source dataset
uspto-grants-2008_04
Patent number
US07365225B2

Reaction notes

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