Octylamine → HCID 11296895, compound

HRID 902824Notes

Reaction equation

HRID 902824 reaction equation
[CH2:1]([NH2:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].Cl[CH2:11][C:12]1[N:13]=[C:14]([C:17]2[CH:25]=[CH:24][C:20]([C:21](Cl)=[O:22])=[CH:19][CH:18]=2)[S:15][CH:16]=1.[F:26][C:27]([F:38])([F:37])[C:28]1[CH:36]=[CH:35][C:31]([C:32](Cl)=[O:33])=[CH:30][CH:29]=1.C[O:40][C:41](=[O:52])[CH2:42][O:43][C:44]1[CH:49]=[CH:48][C:47]([CH2:50][NH2:51])=[CH:46][CH:45]=1>>[CH2:1]([NH:9][C:21]([C:20]1[CH:24]=[CH:25][C:17]([C:14]2[S:15][CH:16]=[C:12]([CH2:11][N:51]([CH2:50][C:47]3[CH:48]=[CH:49][C:44]([O:43][CH2:42][C:41]([OH:52])=[O:40])=[CH:45][CH:46]=3)[C:32](=[O:33])[C:31]3[CH:35]=[CH:36][C:28]([C:27]([F:38])([F:37])[F:26])=[CH:29][CH:30]=3)[N:13]=2)=[CH:18][CH:19]=1)=[O:22])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

5

Reactant 4

HCID 8143OctylamineHCID 676074-(Trifluoromethyl)benzoyl chlorideHCID 16770770Methyl [4-(aminomethyl)phenoxy]acetateHCID 586936994-[4-(Chloromethyl)-1,3-thiazol-2-yl]benzoyl chloride

Product 1

HCID 11296895HCID 11296895, compound

Procedure

The title compound was prepared following the procedure A using octylamine, 4-[4-(chloromethyl)-1,3-thiazol-2-yl]benzoyl chloride, 4-(trifluoromethyl)benzoyl chloride and methyl[4-(aminomethyl)phenoxy]acetate, acetate salt. M+(ESI): 682.1

Sources & evidence

ORD record
ord-bf753558003d452e824f548af90f8394
Source dataset
uspto-grants-2008_04
Patent number
US07365225B2

Reaction notes

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