HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Chloro-4-nitrophenyl)-2-oxazolidinone → 3-(4-Amino-2-chlorophenyl)-2-oxazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Chloro-4-nitrophenyl)-2-oxazolidinone | HCID 23337318 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(4-Amino-2-chlorophenyl)-2-oxazolidinone | HCID 23337315 | — |
Reaction Steps
A mixture of 24.1 g of 1B and 0.5 g of 10% palladium-on-charcoal catalyst in 150 ml of tetrahydrofuran was treated with hydrogen in a Parr shaker. The mixture then was filtered to give 3-(4-amino-2-chlorophenyl)-2-oxazolidinone (1C) in solution in the tetrahydrofuran.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04226612 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-ab455c4b446048bcbcd3a6ddfc566da8 |
| Source note | uspto-grants-1980_10 |