Hydrogen Bromide → HCID 88776586, compound

Participants

Reaction Steps

Ethyl N-carbobenzoxy-N-(dibutylthiophosphinylmethyl)-glycine (2 g., 0.0046 mole) was reacted with 36% hydrogen bromide (10 ml) in glacial acetic acid at 0° C. Ether was added and the oily precipitate was isolated by decanting the ether layer. The oil was washed with ether twice, then suspended in benzene and treated with propylene oxide. The solution was concentrated in vacuo to yield ethyl N-(dibutylthiophosphinylmethyl)glycine as an amber oil, ND22 =1.4820.

Provenance & Evidence