Hydrogen Bromide → HCID 88776074, compound

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Reaction Steps

Ethyl N-carbobenzoxy-N-(diethylthiophosphinylmethyl)glycine (1 g., 0.0024 mole) was dissolved in 5 ml. of 30% hydrogen bromide in glacial acetic acid at 0° C. The mixture was stirred for one hour. Ether was added and the oily precipitate was isolated by decanting the ether layer. The oil was washed with ether twice, then suspended in benzene and treated with propylene oxide. The solution was concentrated in vacuo to yield ethyl N-(diethylthiophosphinylmethyl)glycine (0.15 g., 0.0005 mole) as an oil, ND25 =1.4960.

Provenance & Evidence