N-Acetylimidazolidinone → 1-Acetyl-2-(1-isopropyl-3-methyl-5-pyrazolyl) amino-2-imidazoline

HRID 903040Notes

Reaction equation

HRID 903040 reaction equation
[NH2:1][C:2]1[N:6]([CH:7]([CH3:9])[CH3:8])[N:5]=[C:4]([CH3:10])[CH:3]=1.[C:11]([N:14]1[CH2:18][CH2:17][NH:16][C:15]1=O)(=[O:13])[CH3:12]>>[C:11]([N:14]1[CH2:18][CH2:17][N:16]=[C:15]1[NH:1][C:2]1[N:6]([CH:7]([CH3:9])[CH3:8])[N:5]=[C:4]([CH3:10])[CH:3]=1)(=[O:13])[CH3:12]

Participants

3

Reactant 2

HCID 79350N-AcetylimidazolidinoneHCID 1210181-Isopropyl-3-methyl-1H-pyrazol-5-amine

Product 1

HCID 127637891-Acetyl-2-(1-isopropyl-3-methyl-5-pyrazolyl) amino-2-imidazoline

Procedure

5-amino-1-isopropyl-3-methylpyrazole (J. Gen. Chem. USSR 31 234, 1961) (19.3 g.) and 1-acetyl-2-imidazolidinone (20.1 g.) were reacted as described in Example I to give 12.73 g. of product, mp 145°-147° C.

Workup

  1. customto give 12.73 g

Sources & evidence

ORD record
ord-d1c5f0b9e2be415aa17ce3ef7def2d33
Source dataset
uspto-grants-1980_10
Patent number
US04226773

Reaction notes

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