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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903067Generated: October 25, 2026

Hydrochloric Acid → 5-Amino-1(3-trifluoromethylphenyl)-3-methylpyrazole hydrochloride

https://huagongshe.com/reaction/903067

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant3-Amino-2-butenenitrileHCID 70699—
Reactant(3-(Trifluoromethyl)phenyl)hydrazineHCID 98650—
Product5-Amino-1(3-trifluoromethylphenyl)-3-methylpyrazole hydrochlorideHCID 23330495—

Reaction Steps

3-Trifluoromethylphenyl hydrazine (Tetrahedron, 1960, 69) (25.0 g.) was reacted with 3-amino-2-butene nitrile (12.7 g.) as described in Example XLIII to give 36.1 g. product as HCl salt, mp 222°-226°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04226773
Source datasetuspto-grants-1980_10
ORD IDord-b2f0fc12bffa4d31bc08f84b5a26d0dc
Source noteuspto-grants-1980_10