N-acetyl-2-imidazolinone → HCID 12763804, compound

HRID 903077Notes

Reaction equation

HRID 903077 reaction equation
Cl.[NH2:2][C:3]1[N:7]([C:8]2[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=2)[N:6]=[C:5]([CH3:16])[CH:4]=1.[C:17]([N:20]1[CH2:24][C:23](=O)[N:22]=[CH:21]1)(=[O:19])[CH3:18]>>[C:17]([N:20]1[CH2:24][CH2:23][N:22]=[C:21]1[NH:2][C:3]1[N:7]([C:8]2[CH:9]=[CH:10][C:11]([O:14][CH3:15])=[CH:12][CH:13]=2)[N:6]=[C:5]([CH3:16])[CH:4]=1)(=[O:19])[CH3:18]

Participants

3

Reactant 2

HCID 22350258N-acetyl-2-imidazolinoneHCID 75485286HCID 75485286, compound

Product 1

HCID 12763804HCID 12763804, compound

Procedure

5-Amino-3-methyl-1-(4-methoxyphenyl) pyrazole HCl (Farmaco 17, 443, 1962) (23.9 g.) and 1-acetyl-2-imidazolinone (15.4 g.) were reacted as described in Example I to give 14.6 g. of product, mp 129°-131°.

Workup

  1. customto give 14.6 g

Sources & evidence

ORD record
ord-f8e83697891e4580b9702cef5ae31559
Source dataset
uspto-grants-1980_10
Patent number
US04226773

Reaction notes

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