1-benzyl-3-methyl-1H-pyrazol-5-amine → 1-Acetyl-2-(1-benzyl-3-methyl-5-pyrazolyl)amino-2-imidazoline

HRID 903084Notes

Reaction equation

HRID 903084 reaction equation
[NH2:1][C:2]1[N:6]([CH2:7][C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:5]=[C:4]([CH3:14])[CH:3]=1.[C:15]([N:18]1[CH2:22][CH:21]=[N:20][C:19]1=O)(=[O:17])[CH3:16]>>[C:15]([N:18]1[CH2:22][CH2:21][N:20]=[C:19]1[NH:1][C:2]1[N:6]([CH2:7][C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)[N:5]=[C:4]([CH3:14])[CH:3]=1)(=[O:17])[CH3:16]

Participants

3

Reactant 2

HCID 7691461-benzyl-3-methyl-1H-pyrazol-5-amineHCID 699078731-Acetyl-3-imidazolinone

Product 1

HCID 127638081-Acetyl-2-(1-benzyl-3-methyl-5-pyrazolyl)amino-2-imidazoline

Procedure

5-Amino-1-benzyl-3-methylpyrazole (J. Gen. Chem. USSR, 31, 2307, 1961) (17.0 g.) and 1-acetyl-3-imidazolinone (14.0 g.) were reacted as described in Example I to give 11.7 g. of product, mp 148°-149°.

Workup

  1. customto give 11.7 g

Sources & evidence

ORD record
ord-9ab96b77456b4be690a0afa904b32cad
Source dataset
uspto-grants-1980_10
Patent number
US04226773

Reaction notes

Loading…