HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 2-Hydroxy-4-Methoxybenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 2,4-Dihydroxybenzaldehyde | HCID 7213 | — |
| Solvent | Sodium Methoxide | HCID 10942334 | — |
| Product | 2-Hydroxy-4-Methoxybenzaldehyde | HCID 69600 | — |
Reaction Steps
Beta-resorcyl aldehyde (13.8 grams) is dissolved in sodium methoxide (in amount equivalent to 2.3 grams of sodium), and 14.2 grams of methyl iodide are added. The mixture is refluxed for 4 hours. Alcohol (methanol) is distilled off and dilute HCl added. The resulting red liquid is separated from the aqueous layer, dried and steam distilled.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04226792 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-e7923aa21ceb47ccb1d9eb92d56cd4c9 |
| Source note | uspto-grants-1980_10 |