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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903122Generated: November 1, 2026

4-(Chloromethyl)phenylacetic acid → p-Sulfomethylphenylacetic acid

https://huagongshe.com/reaction/903122

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Chloromethyl)phenylacetic acidHCID 10313419—
ReactantSodium BisulfiteHCID 23665763—
Productp-Sulfomethylphenylacetic acidHCID 23337711—

Reaction Steps

To a boiling aqueous solution of sodium bisulfite (1.47 g, 0.0141 mole) is added in portions p-chloromethylphenylacetic acid (2.6 g, 0.0141 mole). The solution is further refluxed for 30 minutes and is then evaporated to dryness to give a quantitative yield of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04226806
Source datasetuspto-grants-1980_10
ORD IDord-5b6ae1c84f78449e897e9205358cb9bc
Source noteuspto-grants-1980_10