HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Isocyanate → 3-[3-(Aminocarbonyl)phenoxy]-N-methyl-1-azetidinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | 3-(3-Azetidinyloxy)benzamide | HCID 12812507 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 3-[3-(Aminocarbonyl)phenoxy]-N-methyl-1-azetidinecarboxamide | HCID 13420168 | — |
Reaction Steps
To a stirring solution of 7.0 g. (0.036 mole) of 3-(3-azetidinyloxy)benzamide in 75 ml. of dry benzene was slowly added 2.0 g. (0.036 mole) of methylisocyanate. Stirring was continued at room temperature for one hour. The solid which separated was filtered and recrystallized from 60% ethanol. The product weighed 6.0 g. (67%) and melted at 238°-240° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04226861 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-ef6347e3bf174c59a1cc80fab2a4d170 |
| Source note | uspto-grants-1980_10 |