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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903163Generated: October 26, 2026

Imidazole → Ethyl p-(1-imidazolylmethyl)cinnamate

https://huagongshe.com/reaction/903163

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazoleHCID 795—
ReactantSodium HydroxideHCID 14798—
Reactant2-Propenoic acid, 3-[4-(bromomethyl)phenyl]-, ethyl esterHCID 24820373—
CatalystSilverHCID 23954—
CatalystSilver NitrateHCID 24470—
SolventDimethylformamideHCID 6228—
ProductEthyl p-(1-imidazolylmethyl)cinnamateHCID 70455277—

Reaction Conditions

Temperature100 °C

Reaction Steps

A suspension of 1.75 g of silver salt of imidazole, which was prepared from imidazole and silver nitrate in a sodium hydroxide solution, and 2.7 g of ethyl p-bromomethylcinnamate in 50 ml of N,N-dimethylformamide was heated at 100° C. for 7 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04226878
Source datasetuspto-grants-1980_10
ORD IDord-00e0085f31a44ebb9e93f42425277db0
Source noteuspto-grants-1980_10