Iodine → HCID 53818980, compound

HRID 903165Notes

Reaction equation

HRID 903165 reaction equation
II.[I-].[K+].[SH:5][C:6](=[CH:10][C:11]1[O:12][CH:13]=[CH:14][CH:15]=1)[C:7]([OH:9])=[O:8]>O.C(#N)C>[O:12]1[CH:13]=[CH:14][CH:15]=[C:11]1[CH:10]=[C:6]([S:5][S:5][C:6](=[CH:10][C:11]1[O:12][CH:13]=[CH:14][CH:15]=1)[C:7]([OH:9])=[O:8])[C:7]([OH:9])=[O:8]

Participants

6

Reactant 3

HCID 807Iodine2×HCID 4875Potassium IodideHCID 115309HCID 115309, compound

Product 1

HCID 53818980HCID 53818980, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolvent2×HCID 6342AcetonitrileSolvent

Procedure

Iodine is added to a solution of 100 g of potassium iodide in 500 ml of water to saturation. This saturated solution is added dropwise to a solution of α-mercapto-β-(2-furyl)acrylic acid in 500 ml of acetonitrile and 30 ml of water until the color of iodine persists. The crude product which precipitates is recrystallized from methanol. M.P. 215° C.

Workup

  1. customThe crude product which precipitates
  2. customis recrystallized from methanol

Sources & evidence

ORD record
ord-6c7f75c37b49474c83e1e00364b63175
Source dataset
uspto-grants-1980_10
Patent number
US04226882

Reaction notes

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