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HRID 903169作成日：2026年10月25日

2-{[2-Chloro-4-(trifluoromethyl)phenyl]amino}-3-methylbutanoic acid → Cyano[6-(3-fluorophenoxy)-2-pyridyl]methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate

https://huagongshe.com/reaction/903169

反応式

関与物質

役割名称HCID仕込み量
反応物2-{[2-Chloro-4-(trifluoromethyl)phenyl]amino}-3-methylbutanoic acidHCID 3947643—
反応物Cyano[6-(3-fluorophenoxy)-2-pyridyl]methanolHCID 12879153—
溶媒Diethyl EtherHCID 3283—
生成物Cyano[6-(3-fluorophenoxy)-2-pyridyl]methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoateHCID 54101824—

反応手順

The acid chloride of 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoic acid is reacted with cyano[6-(3-fluorophenoxy)-2-pyridyl]methanol in ether as in Example 2 to give cyano[6-(3-fluorophenoxy)-2-pyridyl]methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04226872
出典データセットuspto-grants-1980_10
ORD IDord-416c17a8043a466fa7aa86dd0fb1ca5f
出典メモuspto-grants-1980_10