2-{[2-Chloro-4-(trifluoromethyl)phenyl]amino}-3-methylbutanoic acid → HCID 54085851, compound

HRID 903173Notes

Reaction equation

HRID 903173 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[NH:12][CH:13]([CH:17]([CH3:19])[CH3:18])[C:14]([OH:16])=[O:15].[C:20]([CH:22]([C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([O:30][C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[N:25]=1)O)#[CH:21]>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[NH:12][CH:13]([CH:17]([CH3:19])[CH3:18])[C:14]([O:16][CH:22]([C:20]#[CH:21])[C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([O:30][C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[N:25]=1)=[O:15]

Participants

3

Reactant 2

HCID 39476432-{[2-Chloro-4-(trifluoromethyl)phenyl]amino}-3-methylbutanoic acidHCID 12800596α-Ethynyl-6-phenoxy-2-pyridinemethanol

Product 1

HCID 54085851HCID 54085851, compound

Procedure

Following the procedure of Example 11, 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoic acid is reacted with α-ethynyl(6-phenoxy-2-pyridyl)methanol to yield the ester, α-ethynyl(6-phenoxy-2-pyridyl)methyl 2-(2-chloro-4-trifluoromethylphenyl-amino)-3-methylbutanoate, MS m/e 502 (M+).

Sources & evidence

ORD record
ord-f3e690207c9b4b8abf76cfcd7ef7e3ec
Source dataset
uspto-grants-1980_10
Patent number
US04226872

Reaction notes

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