6-Phenoxy-2-pyridinemethanol → HCID 23337848, compound

HRID 903177Notes

Reaction equation

HRID 903177 reaction equation
[O:1]([C:8]1[N:13]=[C:12]([CH2:14][OH:15])[CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:16][C:17]1[CH:22]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:20]=[CH:19][C:18]=1[NH:27][CH:28]([CH:32]([CH3:34])[CH3:33])[C:29](O)=[O:30]>>[F:16][C:17]1[CH:22]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:20]=[CH:19][C:18]=1[NH:27][CH:28]([CH:32]([CH3:34])[CH3:33])[C:29]([O:15][CH2:14][C:12]1[CH:11]=[CH:10][CH:9]=[C:8]([O:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[N:13]=1)=[O:30]

Participants

3

Reactant 2

HCID 128791556-Phenoxy-2-pyridinemethanolHCID 202839832-(2-Fluoro-4-trifluoromethylphenylamino)-3-methylbutanoic acid

Product 1

HCID 23337848HCID 23337848, compound

Procedure

(6-Phenoxy-2-pyridyl)methyl 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoate, MS m/e 462 (M+) is prepared using the procedure of Example 1 from (6-phenoxy-2-pyridyl)methanol and the acid chloride of 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoic acid.

Sources & evidence

ORD record
ord-aa7e7bb0ada14eea9516d33dcb52b084
Source dataset
uspto-grants-1980_10
Patent number
US04226872

Reaction notes

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