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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903178Generated: October 30, 2026

2-(4-Chlorophenylamino)-3-methylbutanoic acid → (6-Benzoyl2-pyridyl)methyl 2-(4-chlorophenylamino)-3-methylbutanoate

https://huagongshe.com/reaction/903178

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Chlorophenylamino)-3-methylbutanoic acidHCID 13796079—
Reactant2-(2-Fluoro-4-trifluoromethylphenylamino)-3-methylbutanoic acidHCID 20283983—
Reactant(6-Benzoyl-2-pyridyl)methanolHCID 20293448—
Product(6-Benzoyl2-pyridyl)methyl 2-(4-chlorophenylamino)-3-methylbutanoateHCID 23337850—
Product(6-Benzoyl-2-pyridyl)methyl 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoateHCID 23337857—

Reaction Steps

Following the procedure of Example 1, the acid chloride of each of 2-(4-chlorophenylamino)-3-methylbutanoic acid and 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoic acid is reacted with (6-benzoyl-2-pyridyl)methanol to yield (6-benzoyl2-pyridyl)methyl 2-(4-chlorophenylamino)-3-methylbutanoate and (6-benzoyl-2-pyridyl)methyl 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04226872
Source datasetuspto-grants-1980_10
ORD IDord-f15f905f7005478ba8ac4a686340aa82
Source noteuspto-grants-1980_10