HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 1-Azido-3-acetoxyacetone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 2-Propanone, 1-(acetyloxy)-3-chloro- | HCID 38413 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-Azido-3-acetoxyacetone | HCID 14434780 | — |
Reaction Steps
1-Chloro-3-acetoxyacetone (15.05 g.) is dissolved in tetrahydrofuran (50 ml.) and water (25 ml.) is added. Sodium azide (8.7 g.) is added and the mixture is allowed to stir overnight at room temperature. The reaction mixture is diluted with ether (200 ml.) and the aqueous phase is separated. The organic phase is washed once with brine, then dried and evaporated to give 1-azido-3-acetoxyacetone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04226866 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-cbfc365275df4b84be1e1ffe5a583ae4 |
| Source note | uspto-grants-1980_10 |