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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 9032Generated: October 25, 2026

Dimethylamine → [(2-Chloro-6-fluoro-phenyl)-(2-phenyl-1H-indol-3-yl)-methyl]-dimethylamine

https://huagongshe.com/reaction/9032

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant2-PhenylindoleHCID 13698—
Reactant2-Chloro-6-fluorobenzaldehydeHCID 67847—
Reactant(2-Chloro-6-fluoro-benzylidene)-dimethylammonium chlorideHCID 21985312—
Product[(2-Chloro-6-fluoro-phenyl)-(2-phenyl-1H-indol-3-yl)-methyl]-dimethylamineHCID 21985288—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 2-phenylindole and (2-chloro-6-fluoro-benzylidene)-dimethyl-ammonium chloride, which had been prepared in accordance with example 24 from 2-chloro-6-fluoro-benzaldehyde and dimethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-ab06589450384aad9d4c3c244b329c3c
Source noteuspto-grants-2006_08