Methyl isothiocyanate → HCID 20557579, compound
Reaction equation
[CH3:1][N:2]=[C:3]=[S:4].Cl[CH2:6][C:7]1[N:12]=[CH:11][CH:10]=[CH:9][N:8]=1.[C:13]1(=O)N(CCCS)C(=O)C2=CC=CC=C12.CNC(NCC[CH2:35][S:36][CH2:37][C:38]1N=CC=C[N:39]=1)=S>>[CH3:1][NH:2][C:3]([NH:39][CH2:38][CH2:37][S:36][CH2:35][C:10]1[C:9]([CH3:13])=[N:8][C:7]([CH3:6])=[N:12][CH:11]=1)=[S:4]Participants
5
Procedure
In the procedure of Example 1(i)(b) and (ii), using 2-chloromethylpyrimidine and 3-phthalimidopropanethiol as the starting materials, the product is N-methyl-N'-[3-(2-pyrimidylmethylthio)propyl]thiourea.
Sources & evidence
- ORD record
- ord-a9765cc8c43345dfaf0ab17fbc62fffc
- Source dataset
- uspto-grants-1980_10
- Patent number
- US04226874
Reaction notes
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