Methyl Isocyanate → N-Methyl-N'-[2-(3-pyridazinylmethylthio)ethyl]urea

HRID 903233Notes

Reaction equation

[NH2:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[N:7]=[N:8][CH:9]=[CH:10][CH:11]=1.[CH3:12][N:13]=[C:14]=[O:15]>>[CH3:12][NH:13][C:14]([NH:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[N:7]=[N:8][CH:9]=[CH:10][CH:11]=1)=[O:15]

Participants

Reactant 2

HCID 12228Methyl Isocyanate

HCID 202425053-[(2-Aminoethyl)thiomethyl]pyridazine

Product 1

HCID 20557811N-Methyl-N'-[2-(3-pyridazinylmethylthio)ethyl]urea

Procedure

By the procedure of Example 24, 3-[(2-aminoethyl)thiomethyl]pyridazine is reacted with methyl isocyanate to give the title compound.

Sources & evidence

ORD record: ord-f1777231bde9496d9df81ceec1c5cef6
Source dataset: uspto-grants-1980_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04226874

Reaction notes

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