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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903236Generated: October 30, 2026

Methyl Isocyanate → N-Methyl-N'-[2-(2-pyrimidylmethylamino)ethyl]urea

https://huagongshe.com/reaction/903236

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl IsocyanateHCID 12228—
ReactantN-(2-pyrimidylmethyl)ethylenediamineHCID 20557649—
ProductN-Methyl-N'-[2-(2-pyrimidylmethylamino)ethyl]ureaHCID 20557658—

Reaction Steps

By the procedure of Example 24, N-(2-pyrimidylmethyl)ethylenediamine is reacted with methyl isocyanate to give, after concentrating and separating the residue by column chromatography, the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04226874
Source datasetuspto-grants-1980_10
ORD IDord-aefb9c252d4947eba507f2009bd3abac
Source noteuspto-grants-1980_10