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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903241Generated: October 31, 2026

1,3-Propanediamine → 2-(3-Aminopropylamino)pyrazine

https://huagongshe.com/reaction/903241

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-PropanediamineHCID 428—
ReactantChloropyrazineHCID 73277—
Product2-(3-Aminopropylamino)pyrazineHCID 14397407—

Reaction Steps

Reacting 2-chloropyrazine with 1,3-diaminopropane by the procedure of Example 93 gives 2-(3-aminopropylamino)pyrazine and reacting this intermediate with methyl isothiocyanate gives the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04226874
Source datasetuspto-grants-1980_10
ORD IDord-2a683217c3a0465ea27b2051b41ba33b
Source noteuspto-grants-1980_10