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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903250Generated: October 25, 2026

Benzoyl isothiocyanate → N-benzoyl-N'-[2-(2-thiazolylmethylthio)ethyl]thiourea

https://huagongshe.com/reaction/903250

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl isothiocyanateHCID 68284—
Reactant2-[(Thiazol-2-yl)methylthio]ethylamineHCID 12923403—
ProductN-benzoyl-N'-[2-(2-thiazolylmethylthio)ethyl]thioureaHCID 20557654—

Reaction Steps

By the procedure of Example 18, 2-[(2-aminoethyl)thiomethyl]thiazole is reacted with benzoyl isothiocyanate to give N-benzoyl-N'-[2-(2-thiazolylmethylthio)ethyl]thiourea. Removing the benzoyl group by the procedure of Example 18 gives N-[2-(2-thiazolylmethylthio)ethyl]thiourea. Treating this compound with hydrobromic acid gives the hydrobromide salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04226874
Source datasetuspto-grants-1980_10
ORD IDord-9e1a83a0482d459c9cb3199b2e14cc5d
Source noteuspto-grants-1980_10