6,10-Dimethyl-4-hydroxy-2,5,9-undecatriene → 6,10-Dimethylundeca-2,5,9-trien-4-one

Participants

Reaction Steps

60 g. of the alcohol prepared according to paragraph (b) above, 700 g. of MnO2 and 1800 ml. of CH2Cl2 were stirred for 2 days at 20°-25°. After filtration and evaporation, the distillation of the residue gave 49 g. of crude ketone, b.p. 70°-75°/0.1 Torr, which was purified by vapour phase chromatography using a "20 M Carbowax" column and helium carrier at 140°. nD20 =1.5041; d420 =0.8958.

Provenance & Evidence