HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-formyl-3-(3,4,5-trimethoxyphenyl)propanoate → HCID 20279268, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-formyl-3-(3,4,5-trimethoxyphenyl)propanoate | HCID 3018376 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | Nitroguanidine | HCID 86287517 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 20279268 | HCID 20279268 | 13% |
Reaction Steps
Crude ethyl 2-formyl-3-(3,4,5-trimethoxyphenyl)-propionate (7.41 g) was reacted with nitroguanidine (2.62 g) and sodium methoxide in refluxing methanol for 40 hours to give 2-nitroamino-5-(3,4,5-trimethoxybenzyl)-4-pyrimidone in 13% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04227000 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-c8b93b92ebbf4445a98e7828124d71d2 |
| Source note | uspto-grants-1980_10 |