HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(((2-Aminoethyl)thio)methyl)-5-methylimidazole → HCID 20279278, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(((2-Aminoethyl)thio)methyl)-5-methylimidazole | HCID 665568 | — |
| Reactant | 5-(5,6-Dimethyl-3-pyridylmethyl)-2-nitroamino4-pyrimidone | HCID 12783831 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 20279278 | HCID 20279278 | — |
Reaction Steps
A mixture of 5-(5,6-dimethyl-3-pyridylmethyl)-2-nitroamino-4-pyrimidone and 1.1 molar equivalents of 2-(5-methyl-4-imidazolylmethylthio)ethylamine was heated at 130° for 5 hours and heated under reflux in ethanol for 12 hours, evaporated to dryness and the product isolated as 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-(5,6-dimethyl-3-pyridylmethyl)-4-pyrimidone monohydrate, m.p. 115° (softening at 98°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04227000 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-1440b73f565941528a07d3e5e4f7c93e |
| Source note | uspto-grants-1980_10 |