反应详情

A mixture of 26.4 g. of ethyl N-[4-(8-cyclohexyloctylamino)benzoyl]glycinate, 110 ml. of 1 N sodium hydroxide solution; and 100 ml. of ethanol is stirred at ambient temperature for 2 hours and then partially evaporated. The aqueous solution is washed with diethyl ether, acidified with 6 N hydrochloric acid, and filtered. The white solid is dried in vacuo and recrystallized from acetone to yield the product.

1. additionA mixture of 26.4 g
2. custompartially evaporated
3. washThe aqueous solution is washed with diethyl ether
4. filtrationfiltered
5. customThe white solid is dried in vacuo
6. customrecrystallized from acetone
7. customto yield the product