Potassium ethanethioate → HCID 53709412, compound

HRID 903440Notes

Reaction equation

HRID 903440 reaction equation
Br[CH:2]([C:14](=[O:22])[C:15]1[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=1)[CH2:3][C:4]([N:6]1[CH2:13][CH2:12][CH2:11][C@H:7]1[C:8]([OH:10])=[O:9])=[O:5].[C:23]([O-:26])(=[S:25])[CH3:24].[K+]>C(O)C>[C:23]([S:25][CH:2]([C:14](=[O:22])[C:15]1[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=1)[CH2:3][C:4]([N:6]1[CH2:13][CH2:12][CH2:11][C@H:7]1[C:8]([OH:10])=[O:9])=[O:5])(=[O:26])[CH3:24]

Participants

4

Reactant 2

HCID 23670855Potassium ethanethioateHCID 540519221-[3-Bromo-3-(4-fluorobenzoyl)propionyl]-L-proline

Product 1

HCID 53709412HCID 53709412, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 3.7 g. of 1-[3-bromo-3-(4-fluorobenzoyl)propionyl]-L-proline (Example 19) in 37 ml. of ethanol is added 1.37 g. of potassium thioacetate. The procedure of Example 12 is followed giving the desired product as 1.02 g. of a glass.

Sources & evidence

ORD record
ord-f448e27aa7ad4e09a5557e06c929bc06
Source dataset
uspto-grants-1980_10
Patent number
US04226775

Reaction notes

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