1,1'-Carbonyldiimidazole → HCID 70526171, compound

Participants

Reaction Steps

To a mixture of 4-benzoylcrotonic acid (0.01 mole) in tetrahydrofuran is added 0.01 mole of N,N-carbonyldiimidazole. After stirring for 2 hours, 0.01 mole of L-proline is added. The mixture is stirred for 24 hours to give 1-(4-benzoylcrotonyl)-L-proline. The preceding compound is reacted with thiolacetic acid in carbontetrachloride for 24 hours to give the product of the example as a glass.

Provenance & Evidence