3,4-Dimethylaniline → HCID 4418258, compound

HRID 903475Notes

Reaction equation

HRID 903475 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][C:8]=1[CH3:9])[NH2:5].Cl[C:11]([O:13][CH2:14][CH3:15])=[O:12]>C1C=CC=CC=1>[CH2:14]([O:13][C:11]([NH:5][C:4]1[CH:6]=[CH:7][C:8]([CH3:9])=[C:2]([CH3:1])[CH:3]=1)=[O:12])[CH3:15]

Participants

4

Reactant 2

HCID 72483,4-DimethylanilineHCID 10928Ethyl chloroformate

Product 1

HCID 4418258HCID 4418258, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

The above-named compound is prepared by first dissolving 51.5 grams of 3,4-dimethylaniline in 250 ml. of benzene. Then, while maintaining the solution at a temperature in the range of between 20° C. and 30° C., a benzene solution containing 23.9 grams of ethyl chloroformate is slowly added. The mixture is permitted to stand overnight at room temperature and then filtered. The filtrate is stripped by evaporation under vacuum, leaving the desired product, in the form of a dark purple liquid weighing 30 grams.

Workup

  1. customThe above-named compound is prepared
  2. temperatureThen, while maintaining the solution at a temperature in the range of between 20° C. and 30° C.
  3. additionis slowly added
  4. filtrationfiltered
  5. customThe filtrate is stripped by evaporation under vacuum

Sources & evidence

ORD record
ord-d92946d4492946659692bda0cddae2d0
Source dataset
uspto-grants-1980_10
Patent number
US04227913

Reaction notes

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