Phenyl alpha,beta-epoxy-beta-(3-trifluoromethylphenyl)ethyl ketone → 2-Propanone, 1-phenyl-3-(3-(trifluoromethyl)phenyl)-
Reaction equation
O1[CH:3]([C:4]([CH:6]2[O:8][CH:7]2[C:9]2[CH:14]=[CH:13][CH:12]=[C:11](C(F)(F)F)[CH:10]=2)=O)[CH:2]1[C:19]1C=C[CH:22]=[C:21]([C:25]([F:28])([F:27])[F:26])[CH:20]=1.O1C(C2C=CC=C(C(F)(F)F)C=2)C1C(C1C=CC=CC=1)=O>>[C:9]1([CH2:7][C:6](=[O:8])[CH2:4][C:3]2[CH:2]=[CH:19][CH:20]=[C:21]([C:25]([F:26])([F:27])[F:28])[CH:22]=2)[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1Participants
3
Procedure
Examples 1 and 2 illustrate the production of phenyl alpha, beta-epoxy-beta-(3-trifluoromethylphenyl)ethyl ketone. Examples 3, 4 and 5 illustrate the use of phenyl alpha,beta-epoxy-beta-(3-trifluoromethylphenyl)ethyl ketone to produce 1-phenyl-3-(3-trifluoromethylphenyl)-2-propanone.
Sources & evidence
- ORD record
- ord-b8ae81b1683648899fa16fb1b328dca6
- Source dataset
- uspto-grants-1980_10
- Patent number
- US04228085
Reaction notes
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