HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 23336557, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Diboron | HCID 6328200 | — |
| Reactant | HCID 23336524 | HCID 23336524 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 23336557 | HCID 23336557 | — |
Reaction Steps
N-Acetyl-8-chloro-7-mercapto-1,2,3,4-tetrahydroisoquinoline (24 g., 0.1 m.) is dissolved in tetrahydrofuran and treated with 300 ml. of 1 M diborane (0.3 m.). The mixture is refluxed, cooled, treated with water and then aqueous hydrochloric acid and evaporated to yield 8-chloro-N-ethyl-7-mercapto-1,2,3,4-tetrahydroisoquinoline hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04228170 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-4d3e7bb86bf848089ba9ae1e04908847 |
| Source note | uspto-grants-1980_10 |